Endothelial dysfunction and hypertension.

بررسی تاثیر چهار هفته فعالیت ورزشی ایزومتریک هندگریپ بر تغییرات اتساع عروقی وابسته به جریان خون و فشارخون درزنان مبتلا به پرفشاری خونی

Introduction: Hypertension contributes significantly to worldwide cardiovascular morbidity and mortality. As a matter of fact, hypertension appears to have a complex association with endothelial dysfunction. Hence, the purpose of this study was to evaluate the effect of 4-week isometric handgrip exercise on changes of flow mediated dilation (FMD) and blood pressure within females suffering from...

Endothelial dysfunction and the role of hypertension in Nepalese subjects with major coronary risk factors

Background and Aims: Hypertension is one of the major coronary heart disease risk factors. Endothelial dysfunction is thought to be the preclinical vascular changes in the pathogenesis of atherosclerosis and it its major manifestation; coronary heart disease. This study was designed to assess the endothelial function in subjects with major coronary risk factors including hypertension. Methods: ...

Endothelial Dysfunction in Experimental Models of Arterial Hypertension: Cause or Consequence?

Hypertension is a risk factor for other cardiovascular diseases and endothelial dysfunction was found in humans as well as in various commonly employed animal experimental models of arterial hypertension. Data from the literature indicate that, in general, endothelial dysfunction would not be the cause of experimental hypertension and may rather be secondary, that is, resulting from high blood ...

Endothelial Progenitor Cell Dysfunction in Polycystic Ovary Syndrome: Implications for The Genesis of Cardiovascular Diseases

تأثیر اختلالات گلوکز ناشتا روی فاکتورهای عملکرد اندوتلیال و شاخص‌های بیوشیمیایی در بیماران مبتلا به سندرم متابولیک

 Background & Aims: Endothelial dysfunction is found in early steps of atherosclerosis and is related with diseases such as hypertension, dyslipidemia, and insulin resistance. Insulin resistance is related to metabolic abnormalities .We aimed to examine influence of impaired fasting glucose on endothelial function biomarkers and biochemistry biomarkers in metabolic syndrome patients.Materials &...

TMEM16A Contributes to Endothelial Dysfunction by Facilitating Nox2 NADPH Oxidase-Derived Reactive Oxygen Species Generation in Hypertension.

Ca2+-activated Cl- channels play a crucial role in various physiological processes. However, the role of TMEM16A in vascular endothelial dysfunction during hypertension is unclear. In this study, we investigated the specific involvement of TMEM16A in regulating endothelial function and blood pressure and the underlying mechanism. Reverse transcription-polymerase chain reaction, Western blotting...